Oxidative Stress & Biomarkers

Oxidative Stress reflects awkwardness between the systemic manifestation of receptive oxygen species and a biological system's ability to promptly detoxify the reactive intermediates or to repair the subsequent harm. Disturbances influences in the typical redox condition of cells can cause lethal impacts through the creation of peroxides and free radicals that harm all segments of the cell, including proteins, lipids, and DNA. Oxidative stress from oxidative digestion causes base harm, and also strand softens up DNA. Base harm is for the most part aberrant and caused by receptive oxygen species (ROS) created, O2 (superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). Some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling.

Biomarker generally refers to a measurable indicator of some biological state or condition. The term is also occasionally used to refer to a substance whose detection indicates the presence of an organism. Biomarkers are often measured and evaluated to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. Biomarkers are used in many scientific fields.

  • Exogenous Markers for the characterization of human diseases associated with oxidative stress
  • Electrochemical Methods & ROS Detection: State of the Art & Perspectives
  • Sensors & Biosensors: Next Generation of Oxidative Stress Evaluation
  • Non-invasive Devices to Evaluate Oxidative Stress & Antioxidants
  • Salivary Markers of Oxidative Stress & Antioxidants Status
  • Cellular Signalling

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